The study relevance lies in understanding strategic objectives' content concerning intelligent technologies’ application. The development and application of artificial intelligence in various branches of human activity carry the potential for global changes in society, which, in methodological terms, increases the relevance of considering these problems. The study of ethical problems of artificial intelligence in the concept of sustainable development of society is connected with the dynamic development of innovative artificial intelligence (AI) technologies, which are considered a process of becoming a (...) new technosubject in the context of neuroscience development. The article emphasizes that the development of artificial intelligence acts as an innovative form of technology development when a new kind of human-machine technosubject is formed. The authors identify social problems of artificial intelligence application as the digitalization of life becomes a global anthropological challenge. Innovations of artificial intelligence are directly related to a number of ethical problems, as they contribute not only to the sustainable development of society but also cause dehumanization of relations between people and society. Based on the analysis of qualitative changes in scientific and technological research, using human-machine devices is becoming inevitable. Humankind must develop ethical guidelines for the application of AI systems. (shrink)

The special properties of the Y chromosome stem form the fact that it is a non‐recombining degenerate derivative of the X chromosome. The absence of homologous recombination between the X and the Y chromosome leads to gradual degeneration of various Y chromosome genes on an evolutionary timescale. The absence of recombination, however, also favors the accumulation of transposable elements on the Y chromosome during its evolution, as seen with both Drosophila and mammalian Y chromosomes. Alongside these processes, the acquisition and (...) amplification of autosomal male benefit genes occur. This review will focus on recent studies that reveal the autosome‐acquired genes on the Y chromosome of both Drosophila and humans. The evolution of the acquired and amplified genes on the Y chromosome is also discussed. Molecular and comparative analyses of Y‐linked repeats in the Drosophila melanogaster genome demonstrate that there was a period of their degeneration followed by a period of their integration into RNAi silencing, which was beneficial for male fertility. Finally, the function of non‐coding RNA produced by amplified Y chromosome genetic elements will be discussed. BioEssays 27:1256–1262, 2005. © 2005 Wiley Periodicals, Inc. (shrink)

In this comment, I describe how the processes of free giving can be simulated with the help of the Reflexive Intentional Model of the Subject (RIMS). This simulation demonstrates that there are two essential factors affecting the size of a share given to others: limits accepted by the society as “normal,” and the individual's subjective estimation of a mean share donated by other members of the society.

The new world outlook paradigm of creativity correlates with the fundamental principles of metaphysics and modern natural science. The essential programs of development of science have been formed in Antiquity as the metaphysical principles. For example – principle of continuity VS principle of discreteness of matter;movement as God’s first impulse VS movement as natural attribute of matter. In the field of metaphysics were elaborated the very impotent concepts of modern science – matter, movement, force, atom, corpuscle, energy and others (M. (...) Wartofsky, J. Agassi). Nowadays philosophers and scientists discuss such metaphysical principles as so called antropic principle (S. Hawking, B. Carter); the deep expediency and harmony of physical laws (I. Rosental, Y. Linnick); the principle of synergy and self – organization of nature (I. Prigojin, H. Haken). All these principles may be united in the new metaphysical idea of informational matrix of Universe. (shrink)

This paper sketches an historical outline of philosophy in Russia from the modern era to present time. It describes the main philosophical trends that characterized the ‘Silver Age’ in pre-revolutionary Russia (Cosmism, religious philosophy and early Marxist philosophy), and draws some lines of continuity both with Marxist and pre-Marxist philosophy. It studies the internal evolution and organization of Soviet official philosophical thought, and describes the main features the philosophical Renaissance that took place in the Soviet Union in the second half (...) of the 20th century. It finally describes the main trends, authors and publication of philosophy in Russia today. (shrink)

I focus on the problem of whether a specific biologic basis exists for reinforcing the power of money. I argue in favor of its existence based on a new interpretation of data obtained in experiments with pigeons and rats in an experimental chamber. The experiments demonstrated that in the animals' behavior we can observe some features that had been considered pertinent to human beings only, such as making certain sources of utility “sacred.” (Published Online April 5 2006).

Small non‐coding RNAs (microRNAs or miRs) represent one of the most fertile areas of cancer research and recent advances in the field have prompted us to reconsider the traditional concept of cancer. Some miRs exert negative control over the expression of numerous oncoproteins in normal cells and consequently their deregulation is believed to be an important mechanism underlying cancer development and progression. Owing to their distinct patterns of expression associated with cancer type, remarkable stability and presence in blood and other (...) body fluids, miRs are considered to be highly promising cancer biomarkers. The identification of “miR signatures” associating cancer cell phenotypes with disease outcome and specific risk factor exposures will undoubtedly open new avenues for early diagnosis and therapy of cancer, as well as for the development of novel strategies for cancer prevention. (shrink)

There is given the proof of strict embedding of Leniewski's elementary ontology into monadic second-order calculus of predicates providing a formalization of the class of all formulas valid in all domains (including the empty one). The elementary ontology with the axiom S (S S) is strictly embeddable into monadic second-order calculus of predicates which provides a formalization of the classes of all formulas valid in all non-empty domains.

Non-classical logic via approximation of self-referential sentences by dynamical systems are consistently presented. The new 6-valued truth values (here A=Liar, V=TruthTeller) are presented as a function of the classical truth values xi ∈ {0,1}, which resulted in a philosophical standpoint known as Suszko’s Thesis. Three-valued truth tables were created corresponding to Priest’s tables of the same name. In the process of constructing 4-valued truth tables, two more new truth values (va, av) were revealed that do not coincide with the four (...) original ones. Therefore, the closed tables turned out to be 6-valued. Prof Dunn’s 4-valued truth tables are compared with our 4-valued truth tables. De Morgan’s laws are confirmed by six-valued truth tables. Constructed 3-, 4- and 6-valued lattices obeying De Morgan’s laws. (shrink)

This article analyzes the philosophical views of the Russian philosopher Andrey V. Smirnov. Smirnov has advanced and substantiated the idea that there exist at least two distinct ways of linking th...

We propose that black holes may serve as a physical substratum for intelligent beings, based on(1) The descriptions of brain and psyche are complementary to each other, as internal and external observers of a black hole in the Susskind-t'Hooft's schema.(2) There is an aspect of the inner structure of a black hole that is isomorphic to the structure of the human subjective domain in the psychological model of reflexion.(3) Both black holes and the brain-psyche system have a facet that can (...) be represented using thermodynamic concepts.(4) Both lend themselves to a holographic description. (shrink)

In this study, voluntary and involuntary visual attention focused on different interpretations of a bistable image, were investigated using magnetoencephalography. A Necker cube with sinusoidally modulated pixels' intensity in the front and rear faces with frequencies 6.67 Hz and 8.57 Hz, respectively, was presented to 12 healthy volunteers, who interpreted the cube as either left- or right-oriented. The tags of these frequencies and their second harmonics were identified in the average Fourier spectra of the MEG data recorded from the visual (...) cortex. In the first part of the experiment, the subjects were asked to voluntarily control their attention by interpreting the cube orientation as either being on the left or right. Accordingly, we observed the dominance of the corresponding spectral component, and voluntary attention performance was measured. In the second part of the experiment, the subjects were asked to focus their gaze on a red marker at the center of the cube image without putting forth effort in its interpretation. The alternation of the dominant spectral energies at the second harmonics of the stimulation frequencies was treated as changes in the cube orientation. Based on the results of the first experimental stage and using a wavelet analysis, we developed a method which allowed us to identify the currently perceived cube orientation. Finally, we characterized involuntary attention using the distribution of dominance times when focusing attention on one of the cube orientations, which was related to voluntary attention performance and brain noise. In particular, we confirmed our hypothesis that higher attention performance is associated with stronger brain noise. (shrink)

The author presents two complementary understandings of rationality. He criticizes those who deny the continuing relevance of rationality as a cultural value as well as those who attach exaggerated importance to it.

Any complete understanding of human psychology must take into account that a brain’s actions in the world are mediated by the body it belongs to. In the process of such interaction the human being creates artificial things, structures and mechanisms, such as technology, relationships, and culture. The subjective world is not simply the interactions between neurons at different systemic levels, but the existence of mental contents, which are determined by specific features of a certain domain of reality with which a (...) cognitive agent interacts by means of her actions. It is possible to understand specific features of the subjective world with the conception of the “embodied” and “inactive” cognition. In this framework, the problems of consciousness of consciousness, free will, the possibility of “reading” another mind and constructing mental phenomena are analyzed. If cognitive studies are not used for manipulating humans, and are not means of human degradation they must take into consideration specific features of the human phenomenon: the belonging of the human being to the social world and the world of culture. The development of cognitive studies can lead humans to new levels and contribute to new interpretations of humanism. However, under certain conditions, this development can lead to the death of the human being. This paper shows that some Soviet philosophers and psychologists, during the second half of the twentieth century, anticipated the formulations and solutions of several contemporary key problems in cognitive science before these problems emerged. (shrink)

This article analyzes facts related to the development of modern communication and information technologies and cognitive sciences that call into question the traditions of European culture and philosophy in their understanding of subjectivity: the recognition of the role of consciousness in the performance of activity, the notion of the “Self” as the center of consciousness and decision-making authority, the availability of free will, the idea of human autonomy, and the existence of a private world. The author argues for the need (...) for understanding the phenomenon of consciousness, the Self, and human autonomy in light of modern scientific data, and shows that the human being is impossible without the existence of an autonomous subjective world. (shrink)

The author traces the early evolution of Rubinstein and Shpet from neo-Kantianism and phenomenology, respectively, and shows how their ideas partly converged.

The author shows that the conception of epistemological realism as a contemporary variant of epistemological realism continues the realism tradition and at the same time takes into account some constructivist ideas, giving them a new interpretation. Constructive realism can be a fruitful strategy in cognitive studies, as it gives a philosophical interpretation of the current popular approach in cognitive science: so called “4 E approach”: understanding cognition as embodied, enacted. embedded and extended. The problem of Illusion and Reality is analyzed (...) from the position of constructive realism. The relations between different surrounding worlds of different cognitive agents and the common real world is specially investigated in the context of the opposition between Realism and Relativism. (shrink)

I intend to demonstrate that the usual understanding of the ideals and norms of scientific cognition, which is often considered inseparable from the very notion of science itself, arose in concrete historical conditions; furthermore, these ideals and norms were connected with a certain type of research and a certain type of culture. As we are beginning to realize, such an understanding of ideals and norms does not work in other historical and cultural situations. I also try to show that some (...) interpretations of the ideals and goals of science, as well as some ideas about the world (which were considered pre-scientific) gain new significance in the context of contemporary knowledge. (shrink)

Традиционный философский вопрос о том, затрагивает ли знание реальность или же является лишь конструкцией сознания, получает оригинальный ответ в концепции современного эпистемологического конструктивизма. Этот «конструктивистский реализм» принимает особенно интересную форму в теории восприятия Гибсона, для которого восприятие не является ни построенным, ни просто данным. Скорее оно выступает как результат взаимодействия: познающий субъект вычленяет в реальности то, что соответствует его действиям. Важную роль при этом играет изучение социальной и культурной обусловленности когнитивной деятельности. À la question philosophique traditionnelle de savoir si la (...) connaissance porte sur le réel ou est une simple construction de l’esprit, le constructivisme épistémologique actuel essaye de donner une réponse originale. Ce « réalisme constructiviste » prend une forme particulièrement intéressante dans la théorie de la perception de Gibson, pour qui celle-ci n’est ni construite, ni donnée mais résulte d’une interaction, le sujet connaissant « découpant » dans la réalité ce qui correspond à ses activités. L’étude du conditionnement social et culturel des activités cognitives entre aussi dans ce cadre. To the traditional philosophical question as to know whether knowledge focuses on reality or is merely a mental construct, present day epistemological constructivism tries to give an original answer. This “constructivist realism” is especially interesting in Gibson’s theory of perception, according to which it is neither built nor given but results from an interaction, the knowing subject “cutting” within reality ail that corresponds to its activities. The study of social and cultural conditioning of cognitive activities can also be integrated in this framework. (shrink)

The author considers the social consequences of "converging technologies" and also of the internet and other new social technologies.

Rare copy number variants have a prominent role in the aetiology of schizophrenia and other neuropsychiatric disorders. Substantial risk for schizophrenia is conferred by large CNVs at several loci, including microdeletions at 1q21.1, 3q29, 15q13.3 and 22q11.2 and microduplication at 16p11.2. However, these CNVs collectively account for a small fraction of cases, and the relevant genes and neurobiological mechanisms are not well understood. Here we performed a large two-stage genome-wide scan of rare CNVs and report the significant association of copy (...) number gains at chromosome 7q36.3 with schizophrenia. Microduplications with variable breakpoints occurred within a 362-kilobase region and were detected in 29 of 8,290 patients versus 2 of 7,431 controls in the combined sample. All duplications overlapped or were located within 89 kilobases upstream of the vasoactive intestinal peptide receptor gene VIPR2. VIPR2 transcription and cyclic-AMP signalling were significantly increased in cultured lymphocytes from patients with microduplications of 7q36.3. These findings implicate altered vasoactive intestinal peptide signalling in the pathogenesis of schizophrenia and indicate the VPAC2 receptor as a potential target for the development of new antipsychotic drugs. © 2011 Macmillan Publishers Limited. All rights reserved. (shrink)